Elad is the founder of Navigate Precision Biology, a spin-out of the University of Dundee in the UK. The main focus of the spin-out is the establishment of organoid and 3D cell culture models generated inside their NaviPlate system. NaviPlate produces 384 identical organoids in a single 384-well microplate. It provides an miniaturised automation-friendly organoid platform that can be used to study different diseases and for drug discovery and screening purposes. Models include cancer, bone microtissues for bone mineralisation analysis, heart organoids for Calcium flux oscillations, and kidney and lung organoids to investigate fibrosis.
The PHERAstar is Elad´s go-to instrument for these assays that are typically analysed by fluorescence intensity. The PHERAstar enables Elad to run biological assays that have never been done before in microplates with the highest sensitivity and much faster than an imager. For instance, he can detect life/death in as few as 500 cells/well.
