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From assay development to compound screening

BMG LABTECH microplate readers are ideally suited for drug discovery applications. Learn how the CLARIOstar Plus and PHERAstar FSX can be used.

From assay development to compound screening

BMG LABTECH microplate readers are ideally suited for drug discovery applications. Learn how the CLARIOstar Plus and PHERAstar FSX can be used.

Joao works for lifeArc, a medical research charity involved in translational sciences and specifically focussing on unmet medical problems. Recently, Joao has been involved in a COVID-19 project focussed on the identification of small molecules targeting NSP14, an exonuclease of the coronavirus family. His main aim was to study NSP14, develop a fluorescence-based activity assay and then test compounds against it. For this purpose, he used a CLARIOstar Plus and a PHERAstar FSX, for assay development, and compound screening and assay miniaturisation, respectively. Joao analysed his data with the MARS software.

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