
Screening for novel antibiotics in venom against Staphylococcus aureus
The threat of growing antibiotic resistance is constantly increasing. Find out here how venom fractions are emerging as a beacon of hope in the search for novel antibiotics.
FLUOstar® Omega는 세 가지 측정 모드가 있는 멀티 모드 마이크로플레이트 리더입니다.
초고속 UV / vis 분광기 또는 흡광도 용 필터는 물론 다른 모든 검출 모드에 대해 매우 민감한 필터를 사용합니다. FLUOstar Omega는 생명 과학 분야에 이상적인 플레이트 리더입니다.
FLUOstar Omega는 형광 강도(FRET 및 TRF 포함), 발광(BRET 포함) 및 UV/vis 흡광도의 최대 3가지 검출 모드가 있는 다목적 멀티모드 마이크로플레이트 리더입니다.
The threat of growing antibiotic resistance is constantly increasing. Find out here how venom fractions are emerging as a beacon of hope in the search for novel antibiotics.
Have you heard of dTAG degraders yet? Check out this novel approach in targeted protein degradation and learn how it can be used to identify disease-relevant proteins.
Looking for a method to study intracellular bacterial cytotoxicity? This AppNote presents a novel method based on the monitoring of propidium iodide uptake with the CLARIOstar Plus.
Are you looking for a device to measure sample`s biotoxicity with Aliivibrio fischeri? BMG LABTECH's luminometers fulfil this task and offer additional advantages over the classic cuvette-based analysis.
You want to analyse cellular immune types of single cells but don't have a FACS device? Here we present an alternative microplate-based method and its simplified workflow on the VANTAstar.
Acidification is an important tool of innate immune cells. Read here how the pH sensor pHrodo Red and the CLARIOstar Plus with ACU help to track phagosome acidification in real-time.
Fluorescence intensity - incl. FRET
Luminescence (flash and glow) - incl. BRET
UV/Vis absorbance spectra
Top and bottom reading
Endpoint and kinetic
Sequential multi excitation
Sequential multi emission
Simultaneous Dual Emission (FI and LUM)
Spectral scanning (absorbance)
Ratiometric measurements
6 to 384-well plates, user-definable
LVis Plate with 16 low volume microspots (2 μL)
Robot compatible
High energy xenon flash lamp
Low noise photomultiplier tube
CCD spectrometer
Optical filters: ex and em wheels for 8 filters each
UV/vis absorbance spectrometer: full spectra or 8 distinct wavelengths in < 1 sec/well
Filters
240 - 740 nm or 240 - 900 nm for FI
240 - 740 nm for LUM
Spectrometer
220 - 1000 nm for ABS; wavelength precision: ≤ 0.5 nm
FI
<0.2 fmol/well FITC.
TRF
< 30 amol/well europium.
LUM
< 20 amol/well ATP.
ABS with spectrometer
Selectable spectral resolution: 1, 2, 5, and 10 nm.
OD range: 0 to 4 OD; photometric resolution: 0.001 OD.
Accuracy: < 1% at 2 OD.
Precision: < 0.5% at 1 OD and < 0.8% at 2 OD.
Linearity: ≤ 0.8% at 2.0 OD.
ABS with filters
OD range: 0 to 4 OD
Reproducibility: ±0.010 OD for 0-2 OD range
Flying mode (1 flash)
9 s (96), 16 s (384)
Linear, orbital, and double-orbital with user-definable time and speed
System to inject an atmosphere or to pull a vacuum into the reader
+4 °C above ambient up to 45 °C or 65 °C
The upper heating plate of the incubation chamber operates at 0.5 °C more than the lower plate. This prevents condensation build-up on the lid or sealer
Multi-user Reader Control and MARS Data Analysis Software included
FDA 21 CFR Part 11 compliant
Width: 44 cm, depth: 48 cm, height: 30 cm; weight: 28 kg
Excitation and emission filter wheels for 8 filters each
Top: liquid-filled light guides
Bottom: fiber optics
Up to 2 built-in reagent injectors
Injection at measurement position (6 to 384-well)
Individual injection volumes for each well (3 to 500 µL)
Variable injection speed up to 420 µL/s
Up to four injection events per well
Reagent back flushing
Sample capacity: sixteen separate microdrop wells for 2 µL samples; one standard cuvette position for up to 1 mL samples
Quality control internal standards (optional): four NIST traceable optical density filters (approximate values of 0.1, 0.3, 0.6 and 1.0 OD); one holmium oxide filter for wavelength accuracy
Dimensions: conforms to SBS standards for microplates
Microplate incubator and shaker
Actively regulates O2 and CO2 - 0.1-20%
Magazines for up to 50 plates - continuous loading feature
Excitation and emission filters
Please contact your local representative for upgrades including options such as detection modes, reagent injectors, etc
LOD = 3 x SD (20 blanks) / slope (6 pt std curve)
Microplates: white for LUM; black for FI; clear for ABS
96 = 96-well microplates
384sv = 384-well small volume microplates
384g = 384-well glass bottom microplates
Intelligent microplate incubation
Microplate handling system
Low-volume measurements
Filters for a wide range of applications
Functional Microplate Reader Validation
Enhanced cell-based assays
Fluorescence intensity - incl. FRET
Luminescence (flash and glow) - incl. BRET
UV/Vis absorbance spectra
Top and bottom reading
Endpoint and kinetic
Sequential multi excitation
Sequential multi emission
Simultaneous Dual Emission (FI and LUM)
Spectral scanning (absorbance)
Ratiometric measurements
6 to 384-well plates, user-definable
LVis Plate with 16 low volume microspots (2 μL)
Robot compatible
High energy xenon flash lamp
Low noise photomultiplier tube
CCD spectrometer
Optical filters: ex and em wheels for 8 filters each
UV/vis absorbance spectrometer: full spectra or 8 distinct wavelengths in < 1 sec/well
Filters
240 - 740 nm or 240 - 900 nm for FI
240 - 740 nm for LUM
Spectrometer
220 - 1000 nm for ABS; wavelength precision: ≤ 0.5 nm
FI
<0.2 fmol/well FITC.
TRF
< 30 amol/well europium.
LUM
< 20 amol/well ATP.
ABS with spectrometer
Selectable spectral resolution: 1, 2, 5, and 10 nm.
OD range: 0 to 4 OD; photometric resolution: 0.001 OD.
Accuracy: < 1% at 2 OD.
Precision: < 0.5% at 1 OD and < 0.8% at 2 OD.
Linearity: ≤ 0.8% at 2.0 OD.
ABS with filters
OD range: 0 to 4 OD
Reproducibility: ±0.010 OD for 0-2 OD range
Flying mode (1 flash)
9 s (96), 16 s (384)
Linear, orbital, and double-orbital with user-definable time and speed
System to inject an atmosphere or to pull a vacuum into the reader
+4 °C above ambient up to 45 °C or 65 °C
The upper heating plate of the incubation chamber operates at 0.5 °C more than the lower plate. This prevents condensation build-up on the lid or sealer
Multi-user Reader Control and MARS Data Analysis Software included
FDA 21 CFR Part 11 compliant
Width: 44 cm, depth: 48 cm, height: 30 cm; weight: 28 kg
Excitation and emission filter wheels for 8 filters each
Top: liquid-filled light guides
Bottom: fiber optics
Up to 2 built-in reagent injectors
Injection at measurement position (6 to 384-well)
Individual injection volumes for each well (3 to 500 µL)
Variable injection speed up to 420 µL/s
Up to four injection events per well
Reagent back flushing
Sample capacity: sixteen separate microdrop wells for 2 µL samples; one standard cuvette position for up to 1 mL samples
Quality control internal standards (optional): four NIST traceable optical density filters (approximate values of 0.1, 0.3, 0.6 and 1.0 OD); one holmium oxide filter for wavelength accuracy
Dimensions: conforms to SBS standards for microplates
Microplate incubator and shaker
Actively regulates O2 and CO2 - 0.1-20%
Magazines for up to 50 plates - continuous loading feature
Excitation and emission filters
Please contact your local representative for upgrades including options such as detection modes, reagent injectors, etc
LOD = 3 x SD (20 blanks) / slope (6 pt std curve)
Microplates: white for LUM; black for FI; clear for ABS
96 = 96-well microplates
384sv = 384-well small volume microplates
384g = 384-well glass bottom microplates